How do you know how much medication to give me?

The ASA definiton of anesthesia goes on to state: "Because sedation is a continuum, it is not always possible to predict how a each patient will respond." The abililty to measure (i.e. the BIS®) is superior to trying to predict an individual's response to medication. Typically, the propofol is given as a slow, continuous, intravenous infusion to achieve and maintain a BIS® level between 60-70 on a scale of 0 to 100. The added bonus of the slow induction is that patients do not experience the intense sensation of being 'put out.' Many have commented that the 'going to sleep' part was the best.